Development of tools for clinical trial information retrieval and Meta-analysis based on R-Shiny: Taking non-small cell lung cancer as an example
10.12092/j.issn.1009-2501.2020.09.004
- VernacularTitle: 基于R-Shiny实现临床试验信息检索及Meta分析的工具开发-以非小细胞肺癌为例
- Author:
Zhaolei YU
1
Author Information
1. School of Public Health Nanjing Medical University
- Publication Type:Journal Article
- Keywords:
Clinical trials;
Meta-analysis;
Shiny framework
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2020;25(9):984-991
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To develop a tool providing the graphical user interface (GUI), which can integrate Meta-analysis and information retrieval from clinical trials. METHODS: The Web application based on the Bootstrap framework was built with the Shiny package of R language, and the information retrieval and meta-analysis functions were implemented based on the R packages of DT, Meta, gemtc, etc. RESULTS: The tool could filter the articles and variables according to the user's requirements, and the information presented in the form of a table. Users can also select different experimental group drugs and control group drugs for classic meta-analysis, and add or subtract different studies to construct the network map between drugs for network meta-analysis. CONCLUSION: This tool has a friendly user interface, which is easy to use, accurate in analysis and drawing results, and can bring convenience to researchers.
