Influence of prenylation at C-8 of ring A of flavonoid on bioactivity of parent compound
10.7501/j.issn.0253-2670.2014.16.026
- Author:
Jiu-Lin YANG
1
Author Information
1. Center for Systems Biomedical Sciences, University of Shanghai for Science and Technology
- Publication Type:Journal Article
- Keywords:
Anti-bone resorption;
Anti-oxidant;
Antimicrobial;
Antitumor;
Flavonoids;
Prenylation
- From:
Chinese Traditional and Herbal Drugs
2014;45(16):2418-2421
- CountryChina
- Language:Chinese
-
Abstract:
The flavonoids with the prenylation on site 8 are a unique class of natural flavonoids. The existence of prenyl-moiety could dramatically increase the lipophilicity and the relevant bioactivities of flavonoids. This review discussed the influences of the prenylation at C-8 of ring A in flavonoids on the activities of antioxidant, anti-bone resorption, antimicrobial activity, anti-tumor activity, and tyrosinase inhibition of the backbone flavonoids.
