Chemical constituents from active fraction in pericarps of Juglans mandshurica
10.7501/j.issn.0253-2670.2014.16.004
- Author:
Yuan-Yuan ZHOU
1
Author Information
1. College of Pharmacy, Heilongjiang University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
(2S)-5, 7, 4'-trihydroxy-dihydroflavonol;
(4S)-4-hydroxy-1-tetralone;
1, 4-dihydroxybenzene;
5-hydroxy-3, 7, 3', 4'-tetrameth- oxyflavone;
Chlorogenic acid;
P-methoxyphenylacetic acid;
Pericarps of Juglans mandshurica Maxim
- From:
Chinese Traditional and Herbal Drugs
2014;45(16):2303-2306
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents from the effective fraction in pericarps of Juglans mandshurica. Methods: The compounds were isolated and purified by various chromatographic methods, including silica gel, Sephadex LH-20, and preparative high performance liquid chromatography. Their structures were elucidated by NMR and MS analyses. Results: Fifteen compounds were obtained and identified as kaempferol (1), oleanolic acid (2), chrysophanol (3), pinostrobin (4), (2S)-onysilin (5), juglanin B (6), (S)-regiolone (7), chlorogenic acid (8), (4S)-4-hydroxy-1-tetralone (9), (4S, 5S, 7R, 8R, 14R)-8, 11-dihydroxy-2, 4-cyclo-eudesmane (10), 5-hydroxy-3, 7, 3', 4'-tetramethoxyflavone (11), (2S)-5, 7, 4'-trihydroxy-dihydroflavonol (12), p-hydroxybenzonic acid (13), p-methoxyphenylacetic acid (14), and 1, 4-dihydroxybenzene (15). Conclusion: Compounds 8-15 are first isolated from the pericarps of J. mandshurica and compounds 11, 12, 14, and 15 are obtained from the plants of Juglans L. for the first time.
