Two new germacrane-type sesquiterpenoids from resin of Commiphora mukul
10.7501/j.issn.0253-2670.2014.16.003
- Author:
Bang-Jiao CHEN
1
Author Information
1. School of Pharmaceutical Sciences, Shandong University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Commiphora mukul (Hook. ex Stocks) Engl.;
Germacrane-type sesquiterpenoids;
Mukulsin A;
Mukulsin B;
Myrrha
- From:
Chinese Traditional and Herbal Drugs
2014;45(16):2299-2302
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents from the resin of Commiphora mukul. Methods: Silica gel and Sephadex LH-20 column chromatographies were used for the purification, and spectroscopic techniques were adopted for the structure elucidation. Results: Two germacrane-type sesquiterpenoids have been isolated from the resin of C. mukul, which were identified to be 1α, 8α, 12α-trihydroxy-2β-methoxy-8, 12-epoxygermacra-7(11), 9-dien-6-one (1) and 1α, 8β, 12α-trihydroxy-2β-methoxy-8, 12- epoxygermacra-7(11), 9-dien-6-one (2). Conclusion: These two sesquiterpenoids are new compounds named as mukulsin A (1) and mukulsin B (2), respectively.
