Low-polarity chemical constituents from Scrophularia dentata grown in Tibet
10.7501/j.issn.0253-2670.2014.20.007
- Author:
Liu-Qiang ZHANG
1
Author Information
1. School of Pharmacy, Shanghai University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
2, 6-dimethoxybenzo- quinone;
3-O-acetyloleanolic acid;
Apigenin;
Low-polarity chemical constituents;
Medioresinol;
Scrophularia dentata Royle ex Benth.;
Syringaresinol
- From:
Chinese Traditional and Herbal Drugs
2014;45(20):2908-2911
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the low-polarity chemical constituents from the whole plants of Scrophularia dentata grown in Tibet. Methods: The compounds were isolated and purified by various column chromatography. Their structures were elucidated by means of spectral analyses (MS, 1H-NMR, and 13C-NMR). Results: Fifteen compounds were isolated and identified as oleanolic acid (1), 3-O-acetyloleanolic acid (2), stigmast-4-en-3-one (3), stigmast-4, 22-dien-3-one (4), 2, 6-dimethoxybenzoquinone (5), cerevisterol (6), cinnamic acid (7), spinasterol (8), β-sitosterol (9), 2-tritriacontanone (10), 2-(4-hydroxyphen-yl)-ethyl 1-dodecyloctadecanoate (11), apigenin (12), chrysoeriol (13), medioresinol (14), and syringaresinol (15). Conclusion: All the compounds are firstly isolated from this plant and compounds 2-6 and 10-15 are isolated from the plants of this genus for the first time.
