A new phenolic glycoside from Li medicine Lihua Bidou Yan Prescription
10.7501/j.issn.0253-2670.2014.17.003
- Author:
Lin DONG
1
Author Information
1. School of Pharmaceutical Sciences, Hainan Medical University
- Publication Type:Journal Article
- Keywords:
Anti-inflammation;
Elaeagnus gonyanthes Benth.;
Ficus pumila L.;
Li medicine;
Lihua Bidou Yan Prescription;
Phenolic glycoside;
Rhyncoside A-4-methly ether;
Rhyncoside C
- From:
Chinese Traditional and Herbal Drugs
2014;45(17):2437-2439
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents of Li medicine Lihua Bidou Yan prescription. Methods: Chemical constituents were isolated by using various column chromatography. The structures were elucidated on the basis of physicochemical constants and spectral analysis. The anti-inflammatory activities of compound 1 were evaluated using LPS-induced RAW 264.7 cells. Results: Two compounds were obtained from Lihua bidou yan Prescription and identified as rhyncoside A-4-methly ether (1) and rhyncoside C (2), respectively. The NO production in LPS-induced RAW264.7 cells was slightly inhibited by compound 1 at a concentration of 50 μmol/L. Conclusion: Compound 1 is a new phenolic glycoside; Compound 2 is obtained from the prescription for the first time. Rhyncoside A-4-methyl ether has anti-inflammatory activity.
