Quality evaluation of Shenqi Sherong Pill
10.7501/j.issn.0253-2670.2014.07.009
- Author:
Yan ZHAO
1
Author Information
1. Shanghai University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Accumulative release percentage;
Acteoside;
Calycosin;
Calycosin-7-glucoside;
Cryptotanshinone;
Dissolution rate;
Echinacoside;
Formononetin;
HPLC;
Protocatechuic aldehyde;
Quality evaluation;
Rosmarinic acid;
Salvianolic acid B;
Shenqi Sherong Pill
- From:
Chinese Traditional and Herbal Drugs
2014;45(7):942-948
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish a quality evaluation method of Shenqi Sherong Pill. Methods: Four types with 10 marker components were determined by HPLC. The dissolution tests were carried out with oaring method, and the accumulative release percentage was calculated. Results: The linear ranges of protocatechuic aldehyde, echinacoside, calycosin-7-glucoside, acteoside, rosmarinic acid, salvianolic acid B, calycosin, formononetin, cryptotanshinone, and tanshinone IIA were 4.14-62.1, 303.8-455.8, 1.0-150.0, 28.2-422.4, 19.0-570.0, 253.2-7596.0, 6.86-205.8, 46.4-1392.0, 54.0-1620.0, and 10.6-318.0 μg. The f2 similarity factor method indicated that the dissolution of Shenqi Sherong Pill with different lot numbers had similarity in the same media. Conclusion: The method is sensitive, stable, practical, and suitable for the quality evaluation of Shenqi Sherong Pills.
