Effect of raw and processed Schisandrae Fructus on tonifying kidney yang
10.7501/j.issn.0253-2670.2014.13.015
- Author:
Hui GAO
1
Author Information
1. College of Pharmacy, Liaoning University of TCM
- Publication Type:Journal Article
- Keywords:
Adenine;
Hormone;
Kidney-yang deficiency;
Processing;
Schisandrae Fructus
- From:
Chinese Traditional and Herbal Drugs
2014;45(13):1889-1893
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To provide the scientific basis for the research and clinical application of "the processed Schisandrae Fructus as a tonic" through comparing the effects of raw, vinegar steaming and wine steaming Schisandrae Fructus on tonifying kidney-yang of mice. Methods: The kidney-yang deficiency mouse model was established by adenine. With Fugui Dihuang Pill as positive control drug, the effects of raw and differently processed Schisandrae Fructus on kidney-yang deficiency mice were compared regarding by the contents of serum cortisol, testosterone, creatinine, the viscera indexes of seminal vesicle, testicle, and the pathological sections of testis and kidney. Results: The raw and differently processed Schisandrae Fructus had certain therapeutic effects on kidney-yang deficiency mice, such as meliorating the hormonal condition and raising the viscera index of kidney-yang deficiency mice. In terms of therapeutic effects, the wine steaming Schisandrae Fructus was the best among the different kinds of Schisandrae Fructus, and the mid-dose was better than others. Conclusion: Both of the processing methods and dosages of Schisandrae Fructus will affect the therapeutic action on kidney-yang deficiency. The wine steaming Schisandrae Fructus is preferred in the treatment for kidney-yang deficiency, and the dosage should be paid attention to.
