Research progress on biodiversity of endophytic actinobacteria in medicinal plants and their bioactive substances
10.7501/j.issn.0253-2670.2014.14.025
- Author:
You-Kun ZHENG
1
Author Information
1. Key Laboratory of Microbial Diversity in Southwest China, Yunnan Institute of Microbiology, Yunnan University
- Publication Type:Journal Article
- Keywords:
Biosynthesis;
Endophytic actinobacteria;
Genetic screening;
Medicinal plant;
Natural bioactive substances
- From:
Chinese Traditional and Herbal Drugs
2014;45(14):2089-2099
- CountryChina
- Language:Chinese
-
Abstract:
Medicinal plants are important bio-resources for human existence and development. Endophytic actinobacteria with rich biodiversity, widely existing inside the tissues of medicinal plants, are important components of plant micro-ecosystems, and some can produce same or similar bioactive substances generated by their host plants. Therefore, utilizing endophytic actinobacteria to produce bioactive substances with antimicrobial and antitumor effects can not only provide a new way for the development of new drugs, but also effectively protect the endangered medicinal plant resources. Furthermore, this process has important ecological significance and economic value. In this review, research advances on the diversity of endophytic actinobacteria, genes related to natural product biosynthesis, and diversity of their natural bioactive substances are summarized, and a reference for the research of endophytic actinobacteria from the medicinal plants is provided.
