Application of metabonomics in study on traditional Chinese medicine
10.7501/j.issn.0253-2670.2015.05.024
- Author:
Shan ZHAO
1
Author Information
1. Key Laboratory of Chinese Materia Medica, Ministry of Education, Heilongjiang University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Chinese medicinal formula;
Metabonomics;
Safety evaluation;
Syndrome and sign;
Traditional Chinese medicine
- From:
Chinese Traditional and Herbal Drugs
2015;46(5):756-765
- CountryChina
- Language:Chinese
-
Abstract:
Metabonomics is an emerging "omics" following genomics, proteomics, and transcriptomics. It has been widely used in the field of life science, and shows hopeful prospects. The principle of metabonomics is to understand the physiological and pathological state of the organism by comprehensive analysis of the metabolites with low relative molecular weight after external stimuli. In the present, metabonomics is widely used in the studies on traditional Chinese medicine (TCM), and provides the strong technical support for the TCM safety evaluation, the material basis and mechanism of Chinese medicinal formula, and understanding the recognition of TCM syndrome and sign.