Observation of curative effect of Compound Sophorae Injection on treatment of radioactive oral mucosa injury with nasopharyngeal carcinoma
10.7501/j.issn.0253-2670.2015.06.017
- Author:
Lei WANG
1
Author Information
1. Department of Oncology, Second People's Hospital of Kashi
- Publication Type:Journal Article
- Keywords:
Clinical effect;
Compound Sophorae Injection;
Nasopharyngeal carcinoma;
Oral mucosa injury;
Radiotherapy
- From:
Chinese Traditional and Herbal Drugs
2015;46(6):875-877
- CountryChina
- Language:Chinese
-
Abstract:
To observe the effect of Compound Sophorae Injection on the treatment of radioactive oral mucosa injury with nasopharyngeal carcinoma, and discuss its security. One hundred and twenty cases of nasopharyngeal carcinoma patients treated in the hospital from June 2011 to April 2014 were selected as the research object, they were treated by radiotherapy treatment and were randomly divided into two groups with 60 cases in each group, the patients in the control group began to be treated with the gargle composed of physiological saline, lidocaine, and dexamethasone in the second week after radiotherapy: The patients in the observation group adopted Compound Sophorae Injection therapy based on the control group with continuous 2 course, then to compare efficacy between the two groups. The mucosal injury in grade I, grade II, grade III, grade IV, and grade V after the radiotherapy occurred in the observation group were 27 cases (45.0%), 19 cases (31.7%), 9 cases (15.0%), 5 cases (8.3%), and 0 cases (0.0%), respectively. The mucosal injury of the patients in the observation group was significantly lower than that of the patients in control group (P < 0.05). Pain of the patients in the observation group was significantly lighter than that of the patients in the control group (P < 0.05). Adverse reactions in the two groups had no significant statistical difference (P > 0.05). Compound Sophorae Injection used in the treatment of radioactive oral mucosa injury with nasopharyngeal carcinoma has better curative effect and can effectively remove pain with the safety application.
