Chemical constituents from flower of Gentiana tibetica
10.7501/j.issn.0253-2670.2015.14.006
- Author:
Yu-Wei LI
1
Author Information
1. College of Chemistry and Environment Protection Engineering, Southwest University for Nationalities
- Publication Type:Journal Article
- Keywords:
6'-O-β-D-glucopyranosyl gentiopicroside;
Gentiana tibetica King ex Hook. f.;
Isoorientin;
Isovitexin;
Saponarin;
Swertiamarine
- From:
Chinese Traditional and Herbal Drugs
2015;46(14):2052-2056
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents in flowers of Gentiana tibetica. Methods: The chemical constituents were isolated from the 95% alcohol extract of G. tibetica flowers by silica column chromatography, Sephadex LH-20, C18 and RP-HPLC. Their chemical structures were elucidated on the basis of IR, ESI-MS, 1H-MNR, and 13C-MNR spectroscopic data. Results: Twelve compounds, including chromene, flavones C-glycosides, secoiridoid glycosides, iridoid glycosides, aliphatic alcohol, and disaccharide, were obtained from the 95% alcohol extract of G. tibetica flowers, Their structures were identified as macrophylloside D (1), orientin 7-caffeate (2), 7-O-feruloylorientin (3), isovitexin (4), saponarin (5), isoorientin (6), 6'-O-β-D-glucopyranosyl gentiopicroside (7), sweroside (8), swertiamarine (9), loganic acid (10), 1-heneicosanol (11), and sucrose (12). Conclusion: Compounds 1-12 are isolated from G. tibetica for the first time.
