Research progress on anti-colorectal cancer effect and mechanism of ginsenosides and their derivatives
10.7501/j.issn.0253-2670.2015.16.024
- Author:
Chen ZHAO
1
Author Information
1. Shenyang Pharmaceutical University
- Publication Type:Journal Article
- Keywords:
Anti-colorectal cancer;
Cell apoptosis;
Cell autophagy;
Cell cycle;
Derivatives;
Ginsenosides
- From:
Chinese Traditional and Herbal Drugs
2015;46(16):2477-2483
- CountryChina
- Language:Chinese
-
Abstract:
Ginsenosides and their derivatives have been shown significant anti-colorectal cancer effect. They exert anti-colorectal cancer effects via inhibiting cancer cell proliferation and migration, blocking cell cycle progression, and inducing cell autophagy and apoptosis. Recently some active studies demonstrated that ginsenosides and their derivatives exhibited a synergistic anti-colorectal cancer effect with the drug. In this study, we summarized the progress in the research of ginsenosides and their derivatives in the treatment of colorectal cancer as well as analyzed their mechanisms, to provide the basis for the discovery and development of targeting anti-colorectal cancer drugs.
