Chemical constituents from seeds of Desmodium styracifolium and their scavenging activity of DPPH free radicals
10.7501/j.issn.0253-2670.2015.17.004
- Author:
Quan YANG
1
Author Information
1. School of Chinese Materia Medica, Guangdong Pharmaceutical University
- Publication Type:Journal Article
- Keywords:
(+)-catechin;
3'-O-methyl epicatechin;
3-O-acetyl (-)-epicatechin;
Desmodium styracifolium (Osb.) Merr.;
DPPH
- From:
Chinese Traditional and Herbal Drugs
2015;46(17):2517-2521
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents from the seeds of Desmodium styracifolium and their activity of scavenging DPPH free radicals. Methods: The compounds were isolated and purified by various column chromatographyic techniques (silica gel, polyamide, sephadex LH-20, etc) and their structures were elucidated by MS and NMR spectral analyses. The activities of scavenging DPPH free radicals from different extracts from the seeds of D. styracifolium were compared. Results: Ten compounds were isolated and identified from the seeds of D. styracifolium, including stigmasterol (1), dibutyl phthalate (2), (+)-catechin (3), benzoic acid (4), 3-hydroxy-2-methyl-4-pyrone (5), 3-O-acetyl (-)-epicatechin (6), afzelin (7), 3'-O-methyl epicatechin (8), kaempferol-7-O-β-D-glucopyranoside (9), and quercetin-3-O-β-D-glucopyranoside (10). Conclusion: Compounds 4-6 and 8 are isolated from the plants of Desmodium Desv. for the first time. Compounds 2, 3, 7, and 9 are isolated from D. styracifolium for the first time. The different extracts from the seeds of D. styracifolium exhibit the certain activity of scavenging DPPH free radicals.
