Clinical observation on therapeutic effect of Yaotongning Capsule on sciatica suffered form cold dampness and blood stasis
10.7501/j.issn.0253-2670.2015.19.016
- Author:
Yan-Ping LIU
1
Author Information
1. Affiliated Hospital of Shanxi University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Adverse effect;
Clinic observation;
Cold dampness and blood stasis syndrome;
Placebo;
Sciatica;
Yaotongning Capsule
- From:
Chinese Traditional and Herbal Drugs
2015;46(19):2916-2918
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the clinical efficacy and safety of Yaotongning Capsule in acute sciatica suffered form cold dampness and blood stasis. Methods: A randomized, double-blind, and placebo controlled trial was performed. One hundred and forty-four patients with sciatica, who were in accordance with the accepting criteria from October 2008 to May 2009, were randomly divided into two groups, 72 cases treated with Yaotongning Capsule in the treatment group and 72 cases treated with placebo in the control group. Patients took five capsules with warm boiled water added yellow rice wine orally half an hour before sleep. The treatment course lasted for 2 weeks. Results: After one course of the treatment, there were significant differences in the curative rate between treatment group and control group. Compared with the control group, the disease control rate in the treatment group was obvious (U=4.138, P < 0.001); So did the pain relief (U=6.330, P < 0.001). And the differences both had statistical significance. There were no remarkable adverse event and side effect in the both groups. Conclusion: Yaotongning Capsule for sciatica suffered form cold dampness and blood stasis has reliable efficacy, safety, and less incident of adverse effects.
