Study on chemical constituents from seeds of Bruceae Fructus
10.7501/j.issn.0253-2670.2015.19.003
- Author:
Qun WANG
1
Author Information
1. School of Traditional Chinese Medicine, Guangdong Pharmaceutical University
- Publication Type:Journal Article
- Keywords:
Brucea javanica (L.) Merr.;
Bruceine D;
Quassinoids;
Yadanziolide A;
Yadanziolide W
- From:
Chinese Traditional and Herbal Drugs
2015;46(19):2839-2842
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents from Bruceae Fructus (the seeds of Brucea javanica). Methods: These compounds were isolated by means of silica gel, ODS, Sephadex LH-20 column chromatographies. Their structures were identified by the methods of high resolution mass spectrometry (HRMS) and NMR spectroscopic analyses. Results: Five quassinoids were isolated from 90% ethanol extract in Bruceae Fructus and identified as yadanziolide W (1), yadanziolide A (2), bruceine D (3), bruceine E (4), javanicolide A (5), respectively. Conclusion: Compound 1 is a new quassinoid which has not been reported in literature.
