Effect of various factors such as habitat, growth period, and commercial specification on antitussive effect of Siraitia grosvenorii
10.7501/j.issn.0253-2670.2015.20.015
- Author:
Hui-Qin TANG
1
Author Information
1. Provincial Key Laboratory of Traditional Chinese Medicine Efficacy, Guangxi University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Antitussive effect;
Commercial specification;
Growth period;
Habitat;
Siraitia grosvenorii (Swingle) C. Jeffrey
- From:
Chinese Traditional and Herbal Drugs
2015;46(20):3051-3054
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the effects of various factors on the antitussive effect of Siraitia grosvenorii. Methods: According to the sequential method (i.e., up and down method) for the principle of median effective dose, the antitussive effect of S. grosvenorii was observed and the median effective time (EDT50) of cough induced by NH3 aq. in mice was calculated. Results: S. grosvenorii from Hunan-Hengyang, Nanning-Tanluo, Yongfu-Longjiang, and Baishou have the antitussive effect, especially in Yongfu-Longjiang and Baishou (R>150%). The fruits obtained from cuttage seedlings and tissue culture seedlings have the antitussive effect, while the immature fruits have not (R<130%). Both the fresh fruit and dried fruit (R>130%) have the significant antitussive effect, and so first class fruit and ringing fruit do (R>130%). However secondary class fruit does not have the antitussive effect (R<130%). Conclusion: The factors, except the habitat, breeding technology, and whether drying or not, such as growth period and commercial specification may influence the antitussive effect of S. grosvenori.
