Chemical constituents from Xisha soft coral Lobophytum sp.
10.7501/j.issn.0253-2670.2015.20.006
- Author:
Jun-Hui LANG
1
Author Information
1. Department of Pharmacy, Changzheng Hospital, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Chiloboterpene A;
Cholest-5,22-dien-3β-ol;
Honulactone A;
Lobophytum sp.;
Sarcophytonone;
Soft coral
- From:
Chinese Traditional and Herbal Drugs
2015;46(20):2999-3003
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the chemical constituents in soft coral Lobophytum sp. collected from the Xisha islands of China. Methods: Compounds were isolated and purified by column chromatographies on silica gel, reversed-phase silica gel (ODS), Sephadex LH-20, and high performance liquid chromatography (HPLC). Their structures were identified on the basis of physicochemical properties and spectroscopic methods. Results: Five compounds were isolated and identified as 11,12-epoxy-sarcophytonin E (1), cholest-5,22-dien-3β-ol (2), honulactone A (3), sarcophytonone (4), and 3-dehydroxyl-20-acetylpresinularolide B (5). Conclusion: Compound 1 is a new compound named as chiloboterpene A. Compounds 2-4 are obtained from the soft coral Lobophytum sp. for the first time.
