Research progress on proteins and peptides from earthworm
10.7501/j.issn.0253-2670.2019.01.036
- VernacularTitle: 地龙蛋白多肽类成分的研究进展
- Author:
Qiao LIU
1
Author Information
1. School of Traditional Chinese Pharmacy, China Pharmaceutical University
- Publication Type:Journal Article
- Keywords:
Anti-stroke activity;
Antibacterial activity;
Anticoagulant activity;
Antifibrotic activity;
Chinese materia medica;
Earthworm;
Peptides;
Proteins
- From:
Chinese Traditional and Herbal Drugs
2019;50(1):252-261
- CountryChina
- Language:Chinese
-
Abstract:
Earthworm is one of animal drugs in Chinese materia medica. It was commonly used in clinic with rich resources in China. Modern studies showed that proteins and peptides were the main components in earthworm. It has been used for treating cardiovascular and cerebrovascular diseases because of its various activities, such as anticoagulant, anti-stroke, antibacterial, and antifibrotic activities, etc. In this review, 48 proteins and peptides from different species of earthworm reported since 1983 were summarized, including their names, molecular weights, amino acid sequences, isoelectric points, and activities. In addition, its pharmacological effects of earthworm proteins and peptides were summarized. In all, it will provide a scientific basis for the further study and comprehensive utilization of proteins and peptides of earthworm.
