The Effects of Preoperative Vaginal Misoprostol on Gastric Contents.
10.4097/kjae.2006.50.6.S28
- Author:
Jeong Yeon HONG
1
;
Myoung Jun KIM
Author Information
1. Department of Anesthesiology and Pain Medicine, Cheil General Hospital and Women's Health Center, Sungkyunkwan University School of Medicine, Seoul, Korea. jenyhongg@hanmail.net
- Publication Type:Original Article
- Keywords:
aspiration pneumonitis;
gastric content;
outpatient surgery;
prostaglandins E
- MeSH:
Ambulatory Surgical Procedures;
Humans;
Hydrogen-Ion Concentration;
Hysteroscopy;
Misoprostol*;
Outpatients;
Pneumonia;
Premedication;
Propofol;
Prostaglandins E
- From:Korean Journal of Anesthesiology
2006;50(6):S28-S30
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: The aim of this study was to evaluate the effect of vaginal misoprostol for operative hysteroscopy on preoperative gastric contents and the risk of acid aspiration pneumonitis. METHODS: Sixty-five patients undergoing operative hysteroscopy who received prophylactic vaginal misoprostol 200 microgram were assigned to the misoprostol group, and sixty-five gynecologic patients without premedication were assigned to the control group. After preoxygenation, a 14-F multiorifice nasogastric tube was inserted for direct aspiration under target-controlled propofol sedation. RESULTS: The mean pH value of gastric fluid was significantly higher in the misoprostol group (2.7 +/- 1.0) than the control group (1.9 +/- 0.7). The mean aspirated volume was (ml) 15.3 +/- 7.4 in the misoprostol group and 16.8 +/- 6.9 in the control group (P > 0.05). There were significantly less patients at high-risk (gastric fluid volumes > 25 ml and pH < 2.5) in the misoprostol group (8/65, 12.3%) than in the control group (18/65, 27.7%). Prophylactic vaginal misoprostol increases the preoperative gastric pH and reduces the number of at high-risk of acid aspiration pneumonitis. CONCLUSIONS: Therefore, vaginal misoprostol for outpatient hysteroscopy may have preventive effect on the acid aspiration pneumonitis.
