New quinoline and anhydride compounds from fruits of Ficus carica
10.7501/j.issn.0253-2670.2019.02.008
- Author:
Wei-Ping YIN
1
Author Information
1. School of Chemical Engineering and Pharmaceutics, Henan University of Science and Technology
- Publication Type:Journal Article
- Keywords:
Ficus carica L.;
Figine G-2;
Figine K-1, figine G-1;
Quinoline
- From:
Chinese Traditional and Herbal Drugs
2019;50(2):318-323
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the chemical constituents of the fruits of Ficus carica. Methods The chemical constituents were isolated and purified with silica gel chromatography, Sephdex LH-20 and HPLC, and their structures were elucidated by spectral analysis including MS, NMR, IR spectroscopic analysis, elment analyzer, and chemical evidence. Results One new quinoline and two new anhydride compounds were isolated from ethyl acetate extract of the fruits of F. carica. The structures of the three new compounds were respectively defined as 4-hydroxyl-6-formyl-8α-methoxyl-quinoline-2-one (1), 5’β,6’α-[(di-ethyl)-5β,6β-cyclohexyl]- epoxyhexyl, cyclo-pentanhydride-[2,2,1]-2α,3β-cycloheptane (2), and 5’β,6’β-[di-(11-methylbutyl,11’-methylbutyl)-9,9’]-cyclo-8’- hexadiene-5α,6α-epoxyhexyl, cyclo-pentanhydride-[2,2,2,1]-2β,3α-cycloheptane (3). Conclusion These compounds were named figine K-1, figine G-1, and figine G-2, respectively.
