Applicatoin progress on click chemistry in targets identification of bioactive components from Chinese materia medica
10.7501/j.issn.0253-2670.2019.04.029
- Author:
Gen LI
1
Author Information
1. School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Bioactive components;
Chinese materia medica;
Click chemistry;
Development of Chinese materia medica;
Target identification
- From:
Chinese Traditional and Herbal Drugs
2019;50(4):984-991
- CountryChina
- Language:Chinese
-
Abstract:
The target is the basis for the active ingredients of Chinese materia medica (CMM), which plays an important role in the patients’ body. Target identification is the key work for the development of CMM. However, the current studies on the target of CMM are still limited, and it has become a bottleneck in the modernization of CMM. Therefore, new ideas and new technologies are required for the research on targets. Recently, a new method for the study of targets has been provided by the technology of activity-based protein profiling represented by click chemistry. The application of click chemistry in target identification of CMM in recent years is briefly reviewed and summarized, and the trends of application and development of click chemistry are prospected in this review.
