Chemical constituents from fruits of Tribulus terrester
10.7501/j.issn.0253-2670.2019.04.004
- Author:
Jie REN
1
Author Information
1. Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center for Cancer, Department of Pharmacy, Tianjin Medical University Cancer Institute and Hospital
- Publication Type:Journal Article
- Keywords:
Caffeic acid methyl ester;
Methyl ferulic acid;
N-p-feruloyltyramine;
Protocatechuic acid methyl ester;
Tribulus terrester L.
- From:
Chinese Traditional and Herbal Drugs
2019;50(4):808-813
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents from the fruits of Tribulus terrester. Methods: The constituents were isolated and purified by silica gel column chromatography, Sephadex LH-20 column chromatography, preparative HPLC and TLC methods. The structures were identified by HR-ESI-MS and spectral analysis methods. Results: Fourteen compounds were isolated from the fruits of Tribulus terrester and the structures were identified as N-p-feruloyltyramine (1), N-trans-p-coumaroyl-3-O- methyldopamine (2), methyl ferulic acid (3), caffeic acid methyl ester (4), protocatechuic acid methyl ester (5), trifilines A (6), 5β-spirost-25(27)-en-3β-ol-12-one 3-O-{β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranoside} (7), tribulosaponin B (8), isoterrestrosin B (9), 25(R)-spirostane-3,5-diene-12-one (10), 25 (R)-spirostane-24β-ol-4-ene-3,12-dione (11), 26-O-β-D-glucopyranosyl-(25S)-5α-furostane-20 (22)-en-12-one-3β,26-diol-3-O-α-L-rhamnopyranosyl-(1→2)-[β-D-glucopyranosyl- (1→4)]-β-D-galactopyranoside (12), terrestrinone A1 (13), and terrestrinone A2 (14). Conclusion: Compounds 1-7 are obtained from the Zygophllyaceae for the first time.
