Research ideas and methods of protein and peptides in animal medicine based on transcriptomics-proteomics-peptidomics integrated association analysis strategy
10.7501/j.issn.0253-2670.2019.05.001
- VernacularTitle: 基于转录组学-蛋白质组学-多肽组学整合关联分析策略的动物药蛋白多肽类成分研究思路及方法
- Author:
Bin YANG
1
Author Information
1. Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Animal medicine;
Peptidomics;
Protein and peptides;
Proteomics;
Transcriptomics
- From:
Chinese Traditional and Herbal Drugs
2019;50(5):1033-1038
- CountryChina
- Language:Chinese
-
Abstract:
Animal medicine is an important part of traditional Chinese medicine, and its unique efficacy is irreplaceable in clinical application. In consideration of the main problems in the research of animal medicine, such as the uncertainty of chemical composition, pharmacodynamic components and toxic components, and the inadequacy of quality control system, this article established a research method of protein and peptides in animal medicine based on transcriptomics-proteomics-peptidomics integrated association analysis strategy, which mainly include the construction of protein database based on transcriptomics, high resolution mass spectrometry analysis, identification and activity evaluation of protein and peptide components. It attempts to provide a practical research method for the analysis and identification of protein and peptide components in animal medicine and technical support for further solving the key issues of animal medicine research.
