Research progress and application strategy on network pharmacology in Chinese materia medica
10.7501/j.issn.0253-2670.2019.10.001
- Author:
Jing XIE
1
Author Information
1. Tianjin University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Application strategy;
Chinese materia medica;
Mechanism;
Network pharmacology;
Research and development of new drug
- From:
Chinese Traditional and Herbal Drugs
2019;50(10):2257-2265
- CountryChina
- Language:Chinese
-
Abstract:
Chinese materia medica (CMM) is a complex system with multiple components, multiple targets and multiple pathways. CMM and its compound prescription for the treatment of diseases follow the thought of holistic view. As an important part in systems biology, network pharmacology is a new subject to reveal the role of traditional Chinese medicine in regulating the organism network at the system level, its characteristics of integrality, systematicness and emphasis on drug interactions are consistent with the basic features of traditional Chinese medicine. It has built a bridge for the study of the relationship between traditional Chinese medicine and modern pharmacology. The paper summarizes the present application status and existing problem of network pharmacology in the field of traditional Chinese medicine, and systematically describes the research thinking, key technology and application method and strategy of network pharmacology. It is the purpose to provide the guidance and reference for the reveal of the modern scientific connotation of traditional Chinese medicine with the network pharmacology.
