Glycosides from roots of Isatis indigotica
10.7501/j.issn.0253-2670.2019.15.009
- VernacularTitle: 板蓝根中糖苷类化学成分研究
- Author:
Dong-Dong ZHANG
1
Author Information
1. School of Pharmacy, Shanghai University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Cannabiside D;
Glycosides;
Isatindigoside C;
Isatis indigotica Fort.;
Progoitrin;
Syringin
- From:
Chinese Traditional and Herbal Drugs
2019;50(15):3575-3580
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the glycosides from the roots of Isatis indigotica. Methods: The chemical components were isolated and purified by silica gel, Sephadex LH-20, ODS C18 gel, and semi preparative-HPLC chromatographic techniques while the structures were deduced by NMR, MS and IR spectral data analysis. Results: A total of 12 glycosides were obtained and elucidated as isatindigoside C (1), epiprogoitrin (2), progoitrin (3), o-aminobenzoic acid 7-O-β-D-glucopyranosyl ester (4), 2’-O-methyladenosine (5), 2-methoxyphenyl β-D-glucopyranoside (6), coniferin (7), syringin (8), cis-coniferin (9), cis-syringin (10), corchoionoside C (11), and cannabiside D (12). Conclusion: Compound 1 is a new indole alkaloid glycoside which named as isatindigoside C, while compounds 5-7 and 9-12 are isolated from the plant for the first time.
