Study on technological conditions of complex extraction of isoliquiritin
10.7501/j.issn.0253-2670.2019.20.012
- Author:
Xiao-Yan SUN
1
Author Information
1. Research Center of Traditional Chinese Medicine Pharmaceutical Technology and Engineering of Gansu Province, Gansu University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Complex extraction;
Isoliquiritin;
Liquorice ultrafiltration;
Sulfonated kerosene;
Trialkyl phosphine oxide
- From:
Chinese Traditional and Herbal Drugs
2019;50(20):4920-4924
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effect of extraction and reverse extraction conditions on the transfer of isoliquiritin. Methods: The extraction rate of isoliquiritin was used as the index to determine the best composition and concentration of complexing extractant. Taking the reverse extraction rate of isoliquiritin as the index, the species and concentration of the reverse extraction agent were investigated, and finally the technological conditions for the extraction and reverse extraction of isoliquiritin from glycyrrhizin ultrafiltration were obtained. Results: The best complexation extraction condition was: the ratio of TRPO to sulfonated kerosene was 7:93, and the extraction rate of isoliquiritin reached 97.60%. The best reverse extraction agent was 0.26% NaOH aqueous solution, and the reverse extraction rate of isoliquiritin reached 95.40%. Conclusion: Under the optimal conditions of extraction and reverse extraction obtained in this experiment, isoliquiritin can be transferred from glycyrrhizin ultrafiltration to complexing extractant and then to alkaline reverse extraction agent, and finally isoliquiritin can be obtained by extraction and reverse extraction.
