Role and significance of anterior cruciate ligament injury in the development of post-traumatic knee osteoarthritis
10.3969/j.issn.2095-4344.2629
- Author:
Guangtao HAN
1
Author Information
1. Department of Orthopedics, Renmin Hospital of Wuhan University
- Publication Type:Journal Article
- Keywords:
Age;
Anterior cruciate ligament injury;
Anterior cruciate ligament reconstruction;
Body mass index;
Cartilage injury;
Graft selection;
Meniscus status;
Time interval between injury and surgery;
Traumatic knee osteoarthritis
- From:
Chinese Journal of Tissue Engineering Research
2020;24(15):2440-2446
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND: Anterior cruciate ligament has the function of stabilizing the knee joint and restricting the tibiofemoral joint in the translation and rotation of the tibia. Most patients with anterior cruciate ligament reconstruction have an increased risk of knee pain and knee instability. Knee osteoarthritis after trauma is a serious complication of anterior cruciate ligament injury. Knee osteoarthritis is a chronic progressive disease, and the mechanism of osteoarthritis after anterior cruciate ligament injury remains unclear. OBJECTIVE: To review the relationship between anterior cruciate ligament injury and the risk factors of post-traumatic knee osteoarthritis, so as to provide guidance for the treatment of post-traumatic knee osteoarthritis. METHODS: The first author searched related articles in PubMed database from the establishment of the database to October 2019. The key words were “ACL injury, traumatic knee osteoarthritis, ACL reconstruction, meniscus status, body mass index, cartilage injury, age, graft selection, time interval between injury and surgery”. A total of 123 articles were retrieved, and 66 articles were eligible for the inclusion criteria. RESULTS AND CONCLUSION: (1) Meniscus status, body mass index, cartilage damage, age, graft selection, and time between injury and surgery may influence the development of post-traumatic knee osteoarthritis. (2) Although anterior cruciate ligament reconstruction is primarily performed to restore stability after anterior cruciate ligament rupture, a long-term goal of the process is to reduce the risk of knee osteoarthritis and maintain long-term joint health. (3) Meniscus resection in patients with anterior cruciate ligament rupture accompanied by meniscus injury is also the cause of knee osteoarthritis, which is likely to be caused by weakened endurance and kinematic changes of the joint.
