A new steroid from leaves of Dysoxylum binectariferum

VernacularTitle: 红果木叶中1个新的甾体类化合物
Author: Zhao LI ¹
Author Information

1. Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences)
Publication Type:Journal Article
Keywords: 2α,3β,4β- trihydroxypregnan-16-one; Dybinstigm A; Dysoxylum binectariferum (Roxb.) Hook. f. ex Bedd; Steroids; Stigmast-5(6)-en-3β,21,22-triol
From: Chinese Traditional and Herbal Drugs 2020;51(19):4896-4901
CountryChina
Language:Chinese
Abstract: Objective: To study the constituents of the leaves of Dysoxylum binectariferum. Methods: The chemical constituents were isolated by various column chromatographic methods, and their structures were identified on the basis of MS and NMR spectral analysis. Results: Five steroids were obtained and their structures were elucidated as stigmast-4(5)-en-3β,6β,22-triol (1), stigmast-5(6)-en-3β,21,22-triol (2), 2α,3β,4β-trihydroxypregnan-16-one (3), 2α,3β-dihydroxy-4β-acetoxypregnan-16-one (4) and 2α,3β-dihydroxypregnan-17(20)-en-16-one (5). Conclusion: Compound 1 is identified as a new compound and named dybinstigm A. Compounds 2-5 are obtained from D. binectariferum for the first time.