Molecular mechanism for telomere-binding proteins in regulating mammalian spermatogenesis
10.3969/j.issn.1674-8115.2018.03.001
- Author:
Chen-Hui HUANG
1
Author Information
1. Shanghai Institute of Precision Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
- Publication Type:Journal Article
- Keywords:
Meiosis;
Spermatogenesis;
Telomere
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2018;38(3):241-242
- CountryChina
- Language:Chinese
-
Abstract:
Telomere attachment to the nuclear envelope and telomere-led chromosomal movement allow proper homologous pairing in mammalian meiotic prophase I. However, the molecular mechanisms for telomere meiosis-specific functions remain to be elucidated. The present review introduced the structure basis for telomere attachment to the nuclear envelope, and revealed a new mechanism by which telomere functions in mammalian spermatogenesis.
