Research progress of microglia and peripheral monocytes in mood disorders
10.3969/j.issn.1674-8115.2018.05.014
- Author:
Rui-Zhi MAO
1
Author Information
1. Division of Mood Disorder, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine
- Publication Type:Journal Article
- Keywords:
Bipolar disorder;
Inflammation;
Major depressive disorder;
Microglia;
Mood disorders;
Peripheral monocyte
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2018;38(5):552-555
- CountryChina
- Language:Chinese
-
Abstract:
The role of inflammation in the pathomechanism and treatment of mood disorders has drawn public attention in the field. As representatives of central and peripheral immune systems, microglia and peripheral monocytic cells become more active and release relative cytokines in mood disorders patients. These two classes of immune cells have similar genetic expression and functions. It is beneficial to explore how microglia and monocytes influence emotion and behavior via immune signaling pathway for understanding the disease pathogenesis and developing potential therapeutic strategies.
