Analysis of dissecting forces in media of human thoracic aorta
- Author:
Yong-Lin QIN
1
Author Information
1. Department of Vascular Surgery
- Publication Type:Journal Article
- From:
Academic Journal of Second Military Medical University
2006;27(10):1118-1120
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish a method for dissecting the tunica media of elastic artery and to analyze the dissecting force between any neighboring 2 layers in the media. Methods: Human thoracic aorta was harvested and the wall of the aorta was dissected into several layers under a stereomicroscope. The dissecting force between each neighboring 2 layers was measured using a stress-strain machine. The ascending aorta and the descending aorta (the upper and lower segments) were given special attention in this study. Results: The wall of the aorta could be dissected at least into 4 layers. The average dissecting force(ADF) between neighboring 2 layers was labeled as ADF (outer), ADF (middle) and ADF (inner) from the adventitia to the intima. For the same interspace on different segments of the aorta, ADF (middle) on the ascending aorta was much higher than that on the upper (P<0.05) and lower descending thoracic aorta(P<0.01); ADF (inner) on the lower descending thoracic aorta was lower than that on the ascending aorta (P<0.01) and upper thoracic aorta (P<0.01); and there was no significant difference in ADF (outer) among 3 sites. For different layers on the same segment, the ADF (outer) was much lower than the ADF (middle) on the ascending aorta (P<0.05); the ADF (inner) was lower than the ADF (outer) (P<0.01) and ADF (middle) (P<0.01) on the lower descending thoracic aorta; and no significant difference was found among all dissecting forces on the upper descending thoracic aorta. Compared with the corresponding longitudinal ADF on the same site, the circumferential ADF (outer) on ascending aorta, ADF (inner) on the upper descending thoracic aorta and the lower descending thoracic aorta were significantly lower (all P<0.05). Conclusion: The tunic media of human thoracic aorta can be dissected into layers and the dissecting forces are not the same on different sites of the aortic wall. Both circumferential and longitudinal dissecting force between the outer 2 layers have no significant changes from the ascending aorta to the descending aorta; those between the middle 2 layers and inner 2 layers are increased from the ascending aorta to the distal part of descending aorta.
