Oxidative stress and cell signal transduction
10.3724/SP.J.1008.2008.00837
- Author:
Peng LIU
1
Author Information
1. Department of Molecular Oncology
- Publication Type:Journal Article
- Keywords:
Oxidative stress;
Reactive oxygen species;
Signal transduction
- From:
Academic Journal of Second Military Medical University
2010;29(7):837-840
- CountryChina
- Language:Chinese
-
Abstract:
Oxidative stress is a major cause of fatty liver, atherosclerosis, cancer, organ damage following ischemia/reperfusion, etc. In recent years, significant improvements have been achieved in studies on signaling pathways involved in oxidative stress, which provide a basis for the drug and gene therapy. This article reviews the major redox-related signaling molecules and pathways, including transcription factors, growth factor signaling, tyrosine kinases and serine/threonine kinases.