Role of toll-like receptors in radioprotection

Author: Chao ZHANG ¹
Author Information

1. Department of Radiation Medicine
Publication Type:Journal Article
Keywords: Hematopoietic stem cells; Interferon type I; Toll-like receptors
From: Academic Journal of Second Military Medical University 2010;31(2):204-206
CountryChina
Language:Chinese
Abstract: Toll-like-receptors (TLRs) have been found to play a critical role in immune response of hosts. They can trigger innate immune responses by detecting pathogen-associated molecular patterns (PAMPs). This paper reviews the roles of several toll-like receptors(TLR4, TLR5, and TLR9) in radioprotection and the related mechanisms, so as to provide theoretical evidences for further studying their roles in radioprotection.