Establishing a scoring formula of liver injury using matter-element analysis for pre-operation evaluation of patients with liver cirrhosis disease
10.3724/SP.J.1008.2012.01227
- Author:
Wei LIU
1
Author Information
1. Department of General Surgery, The first Clinical Medical College, Three Gorges University
- Publication Type:Journal Article
- Keywords:
Child-pugh classification;
Liver cirrhosis;
Liver injury;
Matter-element analysis;
Scoring formula
- From:
Academic Journal of Second Military Medical University
2012;33(11):1227-1230
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish a scoring formula of liver injury (SFLI) using matter-element analysis, so as to provide evidence for preoperative assessment and treatment of patients with liver cirrho sis diseases. Methods: The preoperative serum biochemical indicators of liver cirrhosis patients were collected, including albumin (ALB), prealbumin (PA), total bilirubin (TBIL), serum creatine (SCr), alanine aminotransferase (ALT), aspartate aminotransferase (AST), γ-glutamyl transpeptidase (γ-GT), alkaline phosphatase (ALP), prothrombin time (PT), prothromb in time-international normalized ratio (PT-INR),activated partialthromboplastin time (APTT), and thrombin time (TT). The matter-element analysis was used to establish SFLI, and the results were compared with those of Child liver function system to create SFLI scores. Results: An SFLI was successfully established. The scores of cirrhosis extents were expressed as the R value, which gradually decreased with the aggravation of cirrhosis. R = 1 represented the normal liver tissue; 0. 770≤R
