TIM-l and bronchial asthma
10.3724/SP. J.1008.2012.01135
- Author:
Li-xia QIANG
1
Author Information
1. Department of Respiratory Medicine, Changzheng Hospital, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Asthma;
T cell immunoglobulin and mucin domain molecule 1;
T-lymphocytes cell differentiation
- From:
Academic Journal of Second Military Medical University
2012;33(10):1135-1138
- CountryChina
- Language:Chinese
-
Abstract:
Bronchial asthma is a chronic airway allergy disease involving the imbalance of Th1/Th2. Th2 shift is one of the primary causes of asthma. Recent studies have found that T cell immunoglobulin and mucin domain molecule 1 (TIM-1) play important roles in T cell activation and Th1/Th2 differentiation in asthma, which has been intensively reported in recent researches. This article reviews the characteristics of TIM-1 gene and its role in the pathogenesis of bronchial asthma.
