The 6th and 7th edition TNM staging system in predicting prognosis of gastric cancer patients after operation: A comparative study
10.3724/SP.J.1008.2012.00506
- Author:
Jun HONG
1
Author Information
1. Department of General Surgery, Changhai Hospital, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Prognosis;
Stomach neoplasms;
TNM staging
- From:
Academic Journal of Second Military Medical University
2012;33(5):506-509
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the clinical prognostic value of the 7th edition TNM staging system for gastric cancer patients after operation. Methods The clinical data of 381 gastric cancer patients who received operation in Changhai Hospital during 2002 to 2005 were retrospectively analyzed. And the patients were staged using the 6th and 7th edition of TNM staging system separately. The survival curves of different patients were compared. Results The changes of survival curves were significantly different between different T and N classifications of the 7th edition of TNM staging system (P<0. 05). The changes of survival curves were significantly different in patients with different T2 and T3 classifications and different Ni and N2 classifications in the 7th edition (P<0. 05). The survival rate of IV stage patients in the 6th edition, whose stage was down-regulated in the 7th edition, was significantly higher than those of patients whose stages were not down-regulated in the 7th edition (P<0. 05). Conclusion The 7th edition provides a more detailed and more rational staging for gastric cancer patients than the 6th edition, especially for the T and N staging classification. The 7th edition also has a more accurate prognostic value for gastric cancer patients.