Animal models of traumatic optic neuropathy: Recent advance
10.3724/SP.J.1008.2012.00429
- Author:
Chao LIN
1
Author Information
1. Department of Neurosurgery, Changzheng Hospital, Shanghai Neurosurgical Institute, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Animal models;
Optic nerve injuries
- From:
Academic Journal of Second Military Medical University
2012;33(4):429-431
- CountryChina
- Language:Chinese
-
Abstract:
Traumatic optic neuropathy (TON) is caused by blunt trauma and has poor prognosis due to lack of effective treatments, and it is a main reason for high rate of disability after traumatic brain injury. Progression in neurobiology and molecular biology has made it a research focus to study optic nerve damage and regeneration. This article reviews the advantages and disadvantages of various animal TON models, paving a way for establishing ideal TON models and for future prospective researches.
