RGD-modified polylactide-co-glycolic acid tissue engineering scaffolds for bone regeneration: An advance
10.3724/SP.J.1008.2012.00095
- Author:
Chun TAO
1
Author Information
1. Department of Pharmaceutical Science, School of Pharmacy, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Bone substitutes;
Polylactide-co-glycolic acid;
RGD peptide;
Tissue engineering
- From:
Academic Journal of Second Military Medical University
2012;33(1):95-98
- CountryChina
- Language:Chinese
-
Abstract:
Polylactide-co-glycolic acid (PLGA) tissue engineering scaffolds play an important role in the regeneration of bone and cartilage. Due to the poor hydrophilicity of PLGA, it is difficult for cells to attach to the scaffolds. Modification by RGD (Arg-Gly-Asp) peptides can effectively improve the cellular affinity of PLGA and adhesion and proliferation of the seed cells. This review summarizes the recent progress in PLGA tissue engineering scaffolds modified by RGD peptides.
