Apolipoprotein A5 and atherosclerosis
10.3724/SP.J.1008.2012.00093
- Author:
Zhi-Jia ZHANG
1
Author Information
1. Department of Endocrinology, The 10th People's Hospital of Shanghai, Tongji University School of Medicine
- Publication Type:Journal Article
- Keywords:
Apolipoprotein A5;
Atherosclerosis;
Metabolism of lipids
- From:
Academic Journal of Second Military Medical University
2012;33(1):92-94
- CountryChina
- Language:Chinese
-
Abstract:
Apolipoprotein A5 (ApoA5) is a newly discovered apolipoprotein which is closely associated with high-density lipoprotein (HDL) remodeling. Clinically it demonstrates potent triglyceride reducing effect. Recent studies have found that ApoA5 can increase cholesteroal reverse transportation and HDL function by remodeling HDL, and it can also influence the progression of atherosclerosis in the different ways, showing a potential anti-atherosclerosis effect. Here we briefly review the characteristics of ApoA5 and its potential protective effect against atherosclerosis.
