Value of real-time tissue elastography in differential diagnosis of focal nodular hyperplasia and hepatocellular adenoma

Author: Jun-Feng HONG ¹
Author Information

1. Department of Ultrasonography, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University
Publication Type:Journal Article
Keywords: Adenoma; Elasticity imaging techniques; Focal nodular hyperplasia; Liver diseases; Ultrasonography
From: Academic Journal of Second Military Medical University 2014;35(5):524-528
CountryChina
Language:Chinese
Abstract: Objective: To investigate the value of real-time tissue elastography (RTE) in the differential diagnosis of focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA). Methods: The RTE data of 20 patients with pathologically proven FNH (22 lesions) and 8 patients with HCA (9 lesions) were retrospectively analyzed. The RTE data were evaluated by scores (grades 1-5) and the strain ratios (SR) of the nodules were calculated and compared between the two groups. Results: Most FNH lesions had a grade of 3-4(18/22, 81. 8%)on elastography, while most lesions of HCA had a grade of 1 (5/9, 55. 6%)on elastography, with significant difference found between the two groups (P = 0. 000 2). The strain ratio of FNH was significantly higher than that of HCA(7. 47±4. 53 vs 1. 64±0. 88, P<0. 000 1). Conclusion: The stiffness of FNH in RTE is notably higher than that of HCA, indicating RTE may be a supplementary to routine ultrasonic examination, which may be helpful for differential diagnosis of FNH and HCA.