Bile acid in glucolipid metabolic diseases: An update
10.16781/j.0258-879x.2017.06.0780
- Author:
Yi-Fei HE
1
Author Information
1. Department of Endocrinology, Changhai Hospital, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Bariatric surgery;
Bile acids and salts;
Farnesoid X receptor;
G-protein coupled bile acid receptor;
Nonalcoholic fatty liver disease;
Type 2 diabetes mellitus
- From:
Academic Journal of Second Military Medical University
2017;38(6):780-784
- CountryChina
- Language:Chinese
-
Abstract:
Bile acids, as one of the constituents of bile, can promote the digestion and absorption of fat and cholesterol metabolism. Studies find that bile acid is a signal molecule that not only combines with nuclear hormone receptors such as farnesoid X receptor, and G protein coupled bile acid receptor 5, to regulate their own metabolism, but also plays an important role in diabetes, obesity, non-alcoholic fatty liver disease and other metabolic diseases. The research on its mechanism will provide a solid theoretical basis for the diagnosis and treatment of metabolic diseases. In this review, we summarized the research progress of bile acids in glucolipid metabolic diseases.
