Role of microglia in pathogenesis of depression: An update
10.16781/j.0258-879x.2018.07.0780
- Author:
Jia-Mei LI
1
Author Information
1. Laboratory of Stress Medicine, Faculty of Psychology and Mental Health, Navy Medical University (Second Military Medical University)
- Publication Type:Journal Article
- Keywords:
Depression;
Inflammation;
Microglia;
Neuronal plasticity;
Tryptophan metabolic pathway
- From:
Academic Journal of Second Military Medical University
2018;39(7):780-783
- CountryChina
- Language:Chinese
-
Abstract:
Depression is a common clinical mental disease and has posed a serious threat to human health. Recent studies have found that immune-effecting microglia is closely related to the occurrence of depression. Microglia induces depression through a variety of inflammatory and non-inflammatory mechanisms. It is of great significance to study the role of microglia in the occurrence of depression, which can help to explore new targets of depression treatment and novel antidepressants.
