Research progress of mesenchymal stem cell-derived exosomes in oxidative stress injury
10.16781/j.0258-879x.2018.07.0716
- Author:
Xiao ZHAI
1
Author Information
1. Department of Spine Surgery, Changhai Hospital, Navy Medical University (Second Military Medical University)
- Publication Type:Journal Article
- Keywords:
Damage repair;
Exosomes;
Mesenchymal stem cells;
Oxdative stress
- From:
Academic Journal of Second Military Medical University
2018;39(7):716-721
- CountryChina
- Language:Chinese
-
Abstract:
Oxidative stress damage is known to be a major factor leading to many diseases. Mesenchymal stem cellderived exosomes (MSC-exos) are enriched with various proteins, lipids, coding RNAs and non-coding RNAs, and alleviate oxidative stress damage and stimulate the regeneration response of damaged tissues and cells. MSC-exos hold a great potential for the treatment of diseases caused by oxidative stress. In this review, we summarized the research progress of MSC-exos in cardiovascular injury, lung injury, kidney injury and liver cell injury caused by oxidative stress.