Super “STAR” in translational medicine: Current status and prospects of exosome-related diagnosis and treatment technologies
10.16781/j.0258-879x.2018.07.0697
- Author:
Li LI
1
Author Information
1. Department of Histology and Embryology, College of Basic Medical Sciences, Navy Medical University (Second Military Medical University)
- Publication Type:Journal Article
- Keywords:
Cell communication;
Diagnosis and treatment technology;
Exosomes;
Precision medicine;
Translational medicine
- From:
Academic Journal of Second Military Medical University
2018;39(7):697-703
- CountryChina
- Language:Chinese
-
Abstract:
Recently, exosome has gained great attention in the field of biomedical research, especially in precision medicine-related diagnostic technology and clinical transformation of therapeutic strategies. There have been a large number of exosome-related studies involving non-invasive diagnosis of diseases, liquid biopsy of tumor, development of precision drugs and observation of clinical efficacy. Exosomes possess four biological characteristics: stable, trackable, active and real-time, which make them the key factors for the next generation “STAR” of translational medicine. Since 2014 exosomerelated studies began to show an explosive increase, and several exosome-associated patent technologies or products have appeared. This article summarizes the research history, biological characteristics and clinical exploration of exosomes, and analyzes the prospects of exosome-related technology.