Anti-staphylococcal Effect of a Nephrite-containing Contact Lens Storage Case
10.3341/jkos.2020.61.8.868
- Author:
Su Hwan PARK
1
;
Seung Uk LEE
;
Yoon Kyung KIM
;
Hak Sun YU
;
Sung Hee PARK
;
Jung Hyo AHN
;
Su Jin KIM
;
Jong Hoon SHIN
;
Ji Eun LEE
Author Information
1. Department of Ophthalmology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea
- Publication Type:Original Article
- From:Journal of the Korean Ophthalmological Society
2020;61(8):868-875
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Purpose:To compare the anti-staphylococcal effect of nephrite-containing contact lens (CL) storage cases and conventional CLstorage cases.Method: The degree of proliferation and adhesion of Staphylococcus aureus (S. aureus) on first- to third-generation silicone hydrogelcontact lenses (SHCLs) was analyzed through comparison of 5% nephrite-containing CL storage cases and conventionalCL storage cases. The degree of adhesion of S. aureus to the CL was also compared between 1% or 5% nephrite solution andmultipurpose solution (MPS).Result: Nephrite-containing CL storage cases showed a significant inhibitory effect on S. aureus proliferation (p = 0.004) and significantlyreduced the number of adherent S. aureus on all first- to third generation SHCLs compared with conventional CL storagecases (p = 0.026, p = 0.043, and p = 0.001, respectively). The anti-staphylococcal effect of 1% and 5% nephrite solutionswas not significantly better than that of MPS.
Conclusions:Nephrite shows potential as a next-generation substance for reducing infectious keratitis caused by S. aureuswhen added to CL storage cases.
