Misleading Free Thyroxine (FT4): A Case Report
- Author:
Nurul Hidayah Hashim
1
;
Intan Nureslyna Samsudin
2
;
Ana Dalila Masiman
1
;
Subashini C. Thambiah
2
Author Information
- Publication Type:Case Reports
- Keywords: Hypothyroidism, Immunoassay, Thyroxine, Thyroid function test (TFT)
- From:Malaysian Journal of Medicine and Health Sciences 2020;16(No.2):320-322
- CountryMalaysia
- Language:English
- Abstract: Interpretation of thyroid function test (TFT) is often straightforward but in certain scenarios, discordance between the clinical impression and the laboratory results exists. A 50-year-old woman with a ten years history of hypothyroidism on levothyroxine presented with a recent notable change in TFT [elevated free thyroxine (FT4) and thyroid-stimulating hormone (TSH)], in an otherwise clinically euthyroid and previously stable TFT, leading to levothyroxine being withheld. This case report highlights the possibility of assay interference as a cause of discordant TFT. It also draws the importance of close collaboration between clinicians and the laboratory to avoid unnecessary investigations and inappropriate management of such a case.
- Full text:11.2020my0685.pdf
