The mechanism and treatment of blood-retinal barrier injury
10.3980/j.issn.1672-5123.2020.11.13
- VernacularTitle:血-视网膜屏障损伤的机制及治疗对策
- Author:
Min Li
1
Author Information
1. 1College of Basic Medicine and Life Sciences, Hainan Medical University, Haikou 571199, Hainan Province, China; 2First Clinical College, Hainan Medical University,Haikou 571199, Hainan Province, China; 3Hainan Provincial Key Laboratory of Tropical Brain Research and Transformation, Hainan Medical University, Haikou 571199, Hainan Province, China
- Publication Type:Review
- Keywords:
blood-retinal barrier;
diabetic retinopathy;
acute glaucoma;
retinopathy of prematurity;
tight junction protein;
vascular endothelial growth factor
- From:
International Eye Science
2020;20(11):1902-1906
- CountryChina
- Language:Chinese
-
Abstract:
The blood-retinal barrier(BRB)plays an important role in maintaining the homeostasis of the retinal microenvironment. Many diseases can lead to the damage of BRB, such as diabetic retinopathy, acute glaucoma and retinopathy of prematurity. At present, the molecular mechanism of BRB injury has not been fully explained. This paper briefly reviews the structure and function of blood-retina barrier, the damage mechanism of blood-retina barrier caused by various ocular diseases, and the therapeutic countermeasures of drug therapy, laser therapy and surgical treatment.
- Full text:202011013.pdf
