Evaluation of Anticoagulant Effects of Clinical Pharmacist Management in Anticoagulation Clinic
- VernacularTitle:抗凝门诊临床药师管理的抗凝效果评价
- Author:
Shuyue LI
1
;
Xiang HUI
1
;
Yuanxiang JIN
2
;
Juan WANG
3
;
Huan ZHANG
4
;
Baoyan WANG
5
;
Hang XU
5
Author Information
1. Dept. of Pharmacy，Nanjing Drum Tower Hospital，Nanjing 210008，China;School of Basic Medicine and Clinical Pharmacy，China Pharmaceutical University，Nanjing 210009，China
2. Clinical Pharmacy Laboratory，Huai- hua First People’s Hospital，Hunan Huaihua 418000，China
3. Dept. of Pharmacy，Yili Friendship Hospital，Xinjiang Yili 835000，China
4. Dept. of Pharmacy，Nanjing Tongren Hospital Affiliated to Medical College of Southeast University，Nanjing 211102，China
5. Dept. of Pharmacy，Nanjing Drum Tower Hospital，Nanjing 210008，China
- Publication Type:Journal Article
- Keywords:
Anticoagulation clinic;
Clinical pharmacist;
Anticoagulants;
Grading management;
Warfarin;
NOACs
- From:
China Pharmacy
2020;31(18):2289-2293
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE：To eva luate the anticoagulant effect of clinical pharmacist management in clinic. METHODS ：Retro- spective analysis was performed on medical records of 481 patients in anticoagulant clinic of Nanjing Drum Tower Hospital （herein- after referred as “our hospital ”）from Aug. 2019 to Jan. 2020. The general information （gender，age，patient grading ）of patients ， anticoagulant drug ，anticoagulant causes ，anticoagulant examination [prothrombin time ，international standardized ratio results （INR）]，warfarin dose ，NOACs usage and ADR were recorded. RESULTS ：Totally 481 patients visited anticoagulant clinic of our hospital for 1 587 times in total. The case number of primary ，secondary and tertiary patients were 401，547 and 639，respectively. 470 patients received warfarin ，and 11 patients received NOACs （including 6 cases of riva roxaban，5 cases of dabigatran etexi - . The valve replacement was the main cause of anticoagu - lation（65.28％），followed by atrial fibrillation （14.97％）， valve ring repairment （12.47％）. The main detection method NDYG2017012） of prothrombin time was POCT （83.44％）. Their average dose of warfarin was （3.03±1.28）mg. The average INR of outpa - tients receiving warfarin was 1.99±0.56，and time within treat - E-mail：xiaochongzi78@sina.com ment range （TTR）was 72.79％. The average INR of the first grade was 2.12±0.84 and the TTR was 44.33％；the average INR of the second grade was 1.95±0.52 and the TTR was 72.34％； the average INR of the third grade was 1.94±0.33 and the TTR was 90.42％. There were 102 cases（6.43％）of small bleeding ， and 2 cases（0.13％）of clinical related non major bleeding ；no major bleeding and thromboembolism was observed. CONCLU - SIONS：Clinical pharmacists of anticoagulant clinic in our hospital formulate scientific management and provide individualized con - sultation for patients through implementing hierarchical management of patients. Patients show mild symptoms and low incidence of adverse reactions ；the patients taking warfarin have higher TTR ；clinical pharmacist management has significant anticoagulant effect.
