Recent advances of metal-organic frameworks applied in biomedicine
10.16438/j.0513-4870.2020-0881
- VernacularTitle:金属有机框架在生物医药领域的研究进展
- Author:
Huai-song WANG
1
;
Ya DING
1
Author Information
1. Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing 210009, China
- Publication Type:Research Article
- Keywords:
metal-organic framework;
bio-sensing;
bio-imaging;
isease diagnosis;
isease treatment
- From:
Acta Pharmaceutica Sinica
2020;55(7):1511-1519
- CountryChina
- Language:Chinese
-
Abstract:
Metal-organic frameworks (MOFs) are porous crystalline polymers constructed from the coordination reaction between organic ligands and metal ions. Due to their advantages: adjustable periodic pore structure, large specific surface area and easy functional modification, etc., MOFs have been widely used in the fields of gas storage/separation, catalysis, sensing, biological imaging and drug delivery. In recent years, MOFs have shown great potential in disease diagnosis and treatment. This review summarizes the application of MOFs in the fields of bio-sensing, cell imaging, in vivo imaging, drug delivery, etc., discusses the problems and corresponding solutions in the application of MOFs for biomedicine. We hope this review can provide reference for the designing new methods for disease diagnosis and treatment.
